Journal of Liver Cancer

Ja Kyung Kim

3 Articles

Bronchobiliary Fistula after Transarterial Chemoembolization and Radiotherapyfor Hepatocellular Carcinoma with Bile Duct Invasion: Jungran Choi, Yoomi Park, Kwangwon Rhee, Daewon Ma, Ja Kyung Kim, Jung Il Lee, Kwan Sik Lee, Kwang-Hun Lee, Seokjin Haam; Journal of the Korean Liver Cancer Study Group. 2013;13(2):173-177. Published online September 30, 2013; DOI: https://doi.org/10.17998/jlc.13.2.173

Abstract PDF: Trans-arterial chemoembolization (TACE) is widely used in the treatment of unresectable hepatocellular carcinoma (HCC). Its common complications are right upper quadrant pain, nausea, vomiting, whereas some rare complications include focal pancreatic necrosis, gastric ulcer, renal failure, DIC, biliary tree necrosis and splenic infarction. Bronchobiliary fistula (BBF) is a rare complication that consists of the formation of a passageway between the biliary system and the bronchial tree. We report a case of BBF due to previous TACE for HCC.

A Case of Emergent Treatment for Hemodynamic Unstable Patient with Ruptured Hepatocellular Carcinoma: Jae Keun Kim, Joon Seong Park, Ja Kyung Kim, Hyo Jun Lee, Kwang Hoon Lee, Kwan Sik Lee, Dong Sup Yoon; Journal of the Korean Liver Cancer Study Group. 2012;12(2):160-163. Published online September 30, 2012

Abstract PDF: A ruptured Hepatocellular carcinoma (HCC) is one of life threatening complication and considered as poor prognosis. Hemodynamic stability is a key to the early period survival. Hemostasis can be achieved with transarterial embolization and explo‐laparotomy or surgical resection. Prognosis is related to hemodynamic stability and liver function and tumor size. Surgical resection of ruptured HCC is recommended when it is possible. Further studies are needed for the treatment of recurred and progressive patients with ruptured HCC.

Excellent Response to Hepatic Arterial Infusional Chemotherapy in Advanced Hepatocellular Carcinoma with Portal Vein Thrombosis: Keun-Ho Lee, Ja Kyung Kim, Kwang-Hyub Han, Jong Tae Lee, Do Youn Lee, Jong Yoon Won, Hyun Woong Lee, Hwa Sook Kim, Ki Tae Yoon, Sang Hoon Ahn, Chae Yoon Chon, Young Myoung Moon; Journal of the Korean Liver Cancer Study Group. 2006;6(1):42-46. Published online June 30, 2006

Abstract PDF: There is no treatment of curative aim in advanced hepatocellular carcinoma (HCC) with portal vein thrombosis (PVT), which is associated with poor prognosis. Albeit one of the treatment options is intra-arterial infusional chemotherapy, its therapeutic efficacy was minimal. In this report, we present an unusual case of a patient with favorable result after intra-arterial infusional chemotherapy. This patient was HBV carrier and diagnosed having HCC of stage IVb (T4N0M1) with right PVT on February 1999. Direct right adrenal gland and right kidney invasion and numerous intrahepatic metastases were also noted. The serum AFP level showed more than 60,000 ng/mL, and the Child-Pugh score was 5 (class A). The patient received three sessions of intra-arterial 5-fluorouracil (5-FU) and cisplatin combination chemotherapy and two additional sessions of systemic (5-FU) chemotherapy combined with intra-arterial cisplatin infusion. After total 5 sessions of combination chemotherapy, follow-up CT scan revealed grossly total necrosis of main HCC and numerous intrahepatic metastases, without evidence of viable portion in July 1999. The AFP level decreased to 79.4 ng/mL. The latest CT scan taken in November 2005 also showed no evidence of recurrence. It is noteworthy that the patient with advanced HCC with PVT showed complete remission only after 5 sessions of intra-arterial chemotherapy and the status of complete remission is maintained for more than 76 months.